New research suggests that drugs commonly used for heartburn, acid reflux, and ulcers may raise the risk of numerous fatal conditions, including heart disease and stomach cancer.
woman’s palm holding white and blue pills against yellow background
A new study warns about the dangers of a class of drugs called proton pump inhibitors.
Physicians often prescribe proton pump inhibitors (PPIs) to treat gastrointestinal conditions that involve an excess of acid production.

Nexium, Aciphex, Zegerid, Dexilant, Prevacid, Prilosec, and Protonix are only some of the brand names that PPIs have taken over the years.

More than 15 million people in the United States take prescription PPIs, according to the most recent statistics available, and even more may be taking over-the-counter PPIs.

A new study, appearing in the journal The BMJ, suggests that these drugs may increase the risk of death from various chronic health conditions.

Dr. Ziyad Al-Aly, an assistant professor of medicine at the Washington University School of Medicine in St. Louis, MO, is the senior investigator of the study.

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