Vitamin D supplementation does not reduce the risk of cardiovascular diseases events such as heart attack or stroke, revealed a meta-analysis, combined the results of 21 randomized clinical trials with about 83,000 patients.

Some observational studies have suggested an association between low blood levels of vitamin D and an increased risk of cardiovascular disease events.

The results were similar between different doses of vitamin D and for men and women. A limitation of the study is that the definition of major adverse cardiovascular events varied between the clinical trials.

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